REGULATORY NEWS COMPLIANCE

CDC released on 10/27/2021 a booster dose for those who are immunocompromised who received a 3rd dose.  They can receive a 4th dose as a booster dose 6 months after their 3rd dose

Prevnar 20 Next-gen Pneumococcal Vaccine Approved by FDA

Pfizer's Prevnar 20 has been approved by the FDA back in June. It tackles the same 13 serotypes included in Prevnar 13, plus seven serotypes associated with high fatality rates, antibiotic resistance and meningitis.  So there are now 3 vaccines available for use to help prevent pneumococcal disease: 

Prevnar 13, Pneumovax 23 and now Prevnar 20.

CDC ACIP also Provisionally Recommend Merck’s VAXNEUVANCE (Pneumococcal 15-valent Conjugate Vaccine) in Series with PNEUMOVAX 23 (Pneumococcal Vaccine Polyvalent) as an Option for Pneumococcal Vaccination in Appropriate Adults.

Provisionally the recommended vaccination is a sequential regimen of VAXNEUVANCE followed by PNEUMOVAX 23, or with a single dose of 20-valent pneumococcal conjugate vaccine. These updates would apply to adults who have not previously received a pneumococcal conjugate vaccine or whose previous pneumococcal vaccination history is unknown.

The Series Would be Routinely Recommended Both for Adults 65 Years and Older and for Adults Ages 19 to 64 at Increased Risk for Disease, Such as Those with Certain Underlying Medical Conditions (e.g., chronic conditions such as diabetes, chronic heart disease, chronic lung disease, or chronic liver disease, as well as HIV, an immunocompromising condition) or other disease risk factors (e.g., smoking, alcoholism).

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